Drug safety alert By USFDA: ketoconazole tables use orally to treat Fungal infection on Skin and nail. is associated with loss of lives due to serious liver damage and adrenalin gland abnormalities. USFDA has mentioned brand Nizoral of Pfizer in its drug safety communication on its site. Topical dosage form of drug Ketoconazole is safe for these indications, it donot exhibit such adverse effect like those reported for oral dosage form. This is because toxic metabolites are not generated in liver as drug escapes its first pass metabolism in liver when used topically, and amount of drug passing in to systemic circulation too is low.
Excess Use of Niacin Increases Heart Disease and Stroke Risk
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While niacin (vitamin B3) has traditionally been used to lower cholesterol
and was thought to benefit heart health, recent research suggests a
surprising...
7 months ago